Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 3/20 | 0.64 |
| ▸ | PTGER4 | P35408 | 12/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | LIG1 | P18858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14200098 | 0.85 | APEX1 (0.68) | APEX1PTGER4POLBHSD17B10TDP1 | |
| SCHEMBL21981940 | 0.81 | APEX1 (0.44) | APEX1PTGER4POLBHSD17B10TDP1 | |
| SCHEMBL2844554 | 0.79 | APEX1 (0.66) | APEX1PTGER4POLBHSD17B10TDP1 | |
| SCHEMBL13402277 | 0.78 | APEX1 (1.00) | APEX1PTGER4POLBHSD17B10TDP1 | |
| SCHEMBL13402276 | 0.75 | APEX1 (0.87) | APEX1PTGER4POLBHSD17B10TDP1 | |
| SCHEMBL700764 | 0.71 | APEX1 (0.55) | APEX1PTGER4POLBHSD17B10TDP1 | |
| SCHEMBL3537543 | 0.71 | PTGER4 (1.00) | PTGER4 | |
| SCHEMBL3536487 | 0.70 | PTGER4 (0.84) | PTGER4 | |
| SCHEMBL14620144 | 0.70 | APEX1 (0.53) | APEX1PTGER4POLBHSD17B10TDP1 | |
| SCHEMBL3878729 | 0.69 | KDM4E (0.67) | APEX1POLBHSD17B10MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603893-B1 | EP4 RECEPTOR ANTAGONISTS | ASTERAND UK LTD (GB) | 2008-05-21 | — | — | EP | disclosed |