Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.65 |
| ▸ | S1PR3 | Q99500 | 10/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1420483 | 0.91 | S1PR1 (0.78) | S1PR1S1PR3S1PR5KCNH2 | |
| SCHEMBL1420134 | 0.90 | S1PR1 (0.64) | S1PR1S1PR3S1PR5KCNH2 | |
| SCHEMBL1420600 | 0.89 | S1PR1 (0.81) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1420236 | 0.86 | S1PR1 (0.66) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1420536 | 0.84 | S1PR1 (0.54) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1420566 | 0.81 | S1PR1 (0.51) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1420417 | 0.80 | S1PR1 (0.63) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1420266 | 0.79 | S1PR1 (0.54) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2132488 | 0.79 | S1PR1 (0.57) | S1PR1S1PR3S1PR5KCNH2 | |
| SCHEMBL1420347 | 0.79 | S1PR1 (1.00) | S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297139-A1 | COMPOUNDS | Glaxo Group Limited (GB) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009153307-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-12-23 | — | — | WO | disclosed |