SCHEMBL142018

SCHEMBL142018

CCOC(=O)CC(=O)CCCC(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.54
MGAM O43451 1/20 0.54
SI P14410 1/20 0.54
MGAM2 Q2M2H8 1/20 0.54
TSHR P16473 4/20 0.52
KMT2A Q03164 2/20 0.45
MAPT P10636 1/20 0.45
SLC22A6 Q4U2R8 2/20 0.44
CYP1A2 P05177 1/20 0.44
POLB P06746 2/20 0.43
AKR1B1 P15121 1/20 0.41
SMYD3 Q9H7B4 1/20 0.41
PPARG P37231 5/20 0.40
PPARD Q03181 5/20 0.40
PPARA Q07869 5/20 0.40
HDAC11 Q96DB2 4/20 0.40
GPR84 Q9NQS5 3/20 0.40
ALDH1A1 P00352 2/20 0.40
TLR2 O60603 2/20 0.40
TDP1 Q9NUW8 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1223746 0.88 GAA (0.58) GAAMGAMSIMGAM2TSHR
SCHEMBL11246615 0.88 GAA (0.58) GAAMGAMSIMGAM2TSHR
SCHEMBL6303692 0.86 GAA (0.52) GAAMGAMSIMGAM2TSHR
SCHEMBL4476235 0.85 GAA (0.61) GAAMGAMSIMGAM2TSHR
SCHEMBL6303688 0.85 GAA (0.61) GAAMGAMSIMGAM2TSHR
SCHEMBL21794094 0.85 TSHR (0.48) TSHRKMT2AMAPTSLC22A6AKR1B1
SCHEMBL11226826 0.84 CYP1A2 (0.53) GAAMGAMSIMGAM2TSHR
SCHEMBL17690729 0.84 GAA (0.54) GAAMGAMSIMGAM2TSHR
SCHEMBL11599405 0.84 GAA (0.54) GAAMGAMSIMGAM2TSHR
SCHEMBL6138808 0.83 GAA (0.58) GAAMGAMSIMGAM2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108037200-B Quality detection method of kidney nourishing and tranquilizing pills 广东沙溪制药有限公司 2020-05-12 CN claimed
CN-108037200-A Quality detection method of kidney nourishing and tranquilizing pills 广东益和堂制药有限公司 2018-05-15 CN claimed
CN-1876039-B Detection method of pharmaceutical composition for treating upper respiratory tract infection GUIYANG YUNYAN XICHUANG PHARMACEUTICAL DEV CO LTD 2010-11-17 CN claimed
CN-1876039-A Pharmaceutical composition for treating upper respiratory tract infection, its preparation process and quality control method GUIYANG YUNYAN XICHUANG PHARM (CN) 2006-12-13 CN claimed
EP-4748438-A2 ENTERICALLY DELIVERED BITTER OLIGOPEPTIDES FOR THE TREATMENT FOR TYPE 2 DIABETES Cedars-Sinai Medical Center (US) 2026-05-27 EP disclosed
US-20260137751-A1 ENTERICALLY DELIVERED BITTER OLIGOPEPTIDES FOR THE TREATMENT FOR TYPE 2 DIABETES CEDARS-SINAI MEDICAL CENTER (US) 2026-05-21 US disclosed
EP-4194001-B1 ENTERICALLY DELIVERED BITTER OLIGOPEPTIDES FOR THE TREATMENT OF TYPE 2 DIABETES AND OBESITY CEDARS SINAI MEDICAL CENTER (US) 2026-03-18 EP disclosed
US-12551526-B2 Enterically delivered bitter oligopeptides for the treatment for type 2 diabetes CEDARS-SINAI MEDICAL CENTER (US) 2026-02-17 US disclosed
EP-4194001-A1 ENTERICALLY DELIVERED BITTER OLIGOPEPTIDES FOR THE TREATMENT FOR TYPE 2 DIABETES AND OBESITY Cedars-Sinai Medical Center (US) 2023-06-14 EP disclosed
CN-115963219-A Method for detecting quality of goat milk leaf medicinal material 贵州百灵企业集团制药股份有限公司 2023-04-14 CN disclosed
EP-3285795-B1 ENTERICALLY DELIVERED BITTER OLIGOPEPTIDES FOR THE TREATMENT FOR TYPE 2 DIABETES AND OBESITY CEDARS SINAI MEDICAL CENTER (US) 2022-11-16 EP disclosed
CN-114366802-A Enterally delivered bitter oligopeptides for the treatment of type 2 diabetes 西达-赛奈医疗中心 2022-04-19 CN disclosed
CN-1853674-B Detection method of Xingdan injection GUIYANG YUNYAN XICHUANG PHARMACEUTICAL DEV CO LTD 2010-04-14 CN disclosed
CN-101156893-A Mass control method of apricot red injection GUIYANG YUNYAN XICHUANG PHARM (CN) 2008-04-09 CN disclosed
CN-1939392-A Quality control of Chinese medicine compound preparation QIYUANYIDE DRUG INST BEIJING (CN) 2007-04-04 CN disclosed
CN-1939393-A Quality control of Chinese-medicine compound preparation QIYUANYIDE DRUG INST BEIJING (CN) 2007-04-04 CN disclosed
CN-1876039-A Pharmaceutical composition for treating upper respiratory tract infection, its preparation process and quality control method GUIYANG YUNYAN XICHUANG PHARM (CN) 2006-12-13 CN disclosed
CN-1853674-A Quality Control Method of Xingdan Injection YUNYANXICHUANG DRUG SCIENCE AN (CN) 2006-11-01 CN disclosed
CN-1751718-A Traditional Chinese medicine composition, prepn. method and quality control method therefor CHEN RAN (CN) 2006-03-29 CN disclosed
US-6316605-B1 FOR USE IN RECORDING MATERIALS FOR THERMAL TRANSFER RECORDING, INK JET RECORDING FUJI PHOTO FILM CO., LTD. (JP) 2001-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137751-A1 ENTERICALLY DELIVERED BITTER OLIGOPEPTIDES FOR THE TREATMENT FOR TYPE 2 DIABETES GLP1R, GIPR, NPY2R GAA 1775/4885MGAM 1504/4885SI 123/4885
US-12551526-B2 Enterically delivered bitter oligopeptides for the treatment for type 2 diabetes GLP1R, GIPR, NPY2R GAA 2147/4885MGAM 1362/4885SI 87/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.