Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661726 | 0.85 | XPO1 (0.49) | XPO1HTTMEN1KMT2AMAPT | |
| SCHEMBL381979 | 0.78 | XPO1 (0.44) | XPO1HTTMEN1KMT2AMAPT | |
| SCHEMBL28250552 | 0.76 | AKR1C3 (0.44) | XPO1HTTMEN1KMT2AMAPT | |
| SCHEMBL3361792 | 0.74 | PTGS1 (0.42) | XPO1HTTMEN1KMT2AMAPT | |
| SCHEMBL2961732 | 0.74 | XPO1 (0.44) | XPO1HTTMEN1KMT2AMAPT | |
| SCHEMBL1967302 | 0.74 | HTT (0.53) | XPO1HTTMEN1KMT2AMAPT | |
| SCHEMBL28041722 | 0.72 | XPO1 (0.42) | XPO1HTTMEN1KMT2AMAPT | |
| SCHEMBL11127533 | 0.72 | TSHR (0.43) | XPO1HTTMEN1KMT2AMAPT | |
| SCHEMBL28251094 | 0.72 | IDO1 (0.45) | XPO1HTTMEN1KMT2AMAPT | |
| SCHEMBL6139397 | 0.72 | XPO1 (0.40) | XPO1HTTMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351831-B2 | Process for asymmetric intramolecular [3+2] cyclo-addition of hydrazones | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-04-01 | — | — | US | disclosed |