⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31405357 | 0.57 | — | — | |
| SCHEMBL565093 | 0.57 | — | — | |
| SCHEMBL9449623 | 0.57 | — | — | |
| SCHEMBL2687487 | 0.56 | — | — | |
| SCHEMBL7633133 | 0.56 | — | — | |
| SCHEMBL8958341 | 0.56 | — | — | |
| SCHEMBL11573342 | 0.56 | — | — | |
| SCHEMBL1039320 | 0.52 | — | — | |
| SCHEMBL31375704 | 0.50 | — | — | |
| SCHEMBL8269260 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170305840-A1 | SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARM INNC (US) | 2017-10-26 | — | — | US | disclosed |
| US-9533943-B2 | Substituted tetracycline compounds | PARATEK PHARMACEUTICALS, INC. (US) | 2017-01-03 | — | — | US | disclosed |
| US-20150045329-A1 | SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARMACEUTICALS, INC. (US) | 2015-02-12 | — | — | US | disclosed |
| EP-2319828-A2 | Substituted tetracycline compounds | Paratek Pharmaceuticals, Inc. (US) | 2011-05-11 | — | — | EP | disclosed |
| EP-2319829-A1 | 9-substituted tetracycline compounds | Paratek Pharmaceuticals, Inc. (US) | 2011-05-11 | — | — | EP | disclosed |
| EP-2298323-A2 | Substituted tetracycline compounds | Paratek Pharmaceuticals, Inc. (US) | 2011-03-23 | — | — | EP | disclosed |
| EP-2298322-A2 | Substituted tetracycline compounds | Paratek Pharmaceuticals, Inc. (US) | 2011-03-23 | — | — | EP | disclosed |
| EP-2295404-A2 | Substituted tetracycline compounds | Paratek Pharmaceuticals, Inc. (US) | 2011-03-16 | — | — | EP | disclosed |
| EP-1648859-A2 | SUBSTITUTED TETRACYCLINE COMPOUNDS | Paratek Pharmaceuticals, Inc. (US) | 2006-04-26 | — | — | EP | disclosed |
| US-20050143352-A1 | Substituted tetracycline compounds | PARATEK PHARMACEUTICALS, INC. (US) | 2005-06-30 | — | — | US | disclosed |
| WO-2005009943-A2 | SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARMACEUTICALS, INC. (US) | 2005-02-03 | — | — | WO | disclosed |