Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.63 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1420658 | 0.94 | S1PR1 (0.55) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1420265 | 0.92 | S1PR1 (0.65) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1420437 | 0.91 | S1PR1 (0.75) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1420541 | 0.87 | S1PR1 (0.75) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1420313 | 0.84 | S1PR1 (0.78) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1420177 | 0.84 | S1PR1 (0.55) | S1PR1S1PR3S1PR5 | |
| SCHEMBL10300728 | 0.84 | S1PR1 (0.75) | S1PR1S1PR3S1PR5 | |
| SCHEMBL10300801 | 0.83 | S1PR1 (0.51) | S1PR1S1PR3S1PR5 | |
| SCHEMBL13536131 | 0.83 | S1PR1 (0.53) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1420723 | 0.83 | S1PR1 (0.63) | S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297139-A1 | COMPOUNDS | Glaxo Group Limited (GB) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009153307-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-12-23 | — | — | WO | disclosed |