Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3449368 | 0.94 | S1PR1 (0.72) | S1PR1CYP2D6CYP2C19 | |
| SCHEMBL3451470 | 0.84 | S1PR1 (0.77) | S1PR1CYP2D6CYP2C19 | |
| SCHEMBL3449459 | 0.83 | S1PR1 (0.88) | S1PR1CYP2D6CYP2C19 | |
| SCHEMBL3449910 | 0.82 | S1PR1 (0.84) | S1PR1CYP2D6CYP2C19 | |
| SCHEMBL3449907 | 0.82 | S1PR1 (0.84) | S1PR1CYP2D6CYP2C19 | |
| SCHEMBL3450067 | 0.82 | S1PR1 (0.75) | S1PR1CYP2D6CYP2C19 | |
| SCHEMBL3449688 | 0.81 | S1PR1 (0.76) | S1PR1CYP2D6CYP2C19 | |
| SCHEMBL3450493 | 0.81 | S1PR1 (0.86) | S1PR1CYP2D6CYP2C19 | |
| SCHEMBL3449381 | 0.81 | S1PR1 (0.85) | S1PR1CYP2D6CYP2C19 | |
| SCHEMBL3450719 | 0.81 | S1PR1 (1.00) | S1PR1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008056150-A1 | HETEROCYCLYC SULFONAMIDES HAVING EDG-I ANTAGONISTIC ACTIVITY | ASTRAZENECA AB (SE) | 2008-05-15 | — | — | WO | disclosed |