Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24850243 | 0.94 | MAPT (0.50) | MAPTMMP14TDP1NPC1RAB9A | |
| SCHEMBL30590319 | 0.92 | TDP1 (0.41) | MAPTTDP1NPC1RAB9AKMT2A | |
| SCHEMBL14211447 | 0.92 | TDP1 (0.41) | MAPTTDP1NPC1RAB9AKMT2A | |
| SCHEMBL30819441 | 0.89 | NPC1 (0.39) | MAPTTDP1NPC1RAB9AKMT2A | |
| SCHEMBL30590354 | 0.89 | NPC1 (0.39) | MAPTTDP1NPC1RAB9AKMT2A | |
| SCHEMBL25392005 | 0.87 | MAPT (0.38) | MAPTTDP1NPC1RAB9AKMT2A | |
| SCHEMBL25397302 | 0.87 | TDP1 (0.40) | MAPTTDP1NPC1RAB9AKMT2A | |
| Benzidine SCHEMBL25393276 | 0.84 | TDP1 (0.46) | MAPTTDP1NPC1RAB9AKMT2A | |
| SCHEMBL12714225 | 0.81 | MAPT (0.54) | MAPTKDM4EALDH1A1EGFRERBB2 | |
| SCHEMBL3054212 | 0.81 | EGFR (0.46) | MAPTTDP1KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120307363-A1 | Photo-induced dichroic polarizers and fabrication methods thereof | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) | 2012-12-06 | — | — | US | disclosed |