SCHEMBL14211491

SCHEMBL14211491

OC[C@H]1O[C@H](c2ccc(-c3ccc(-c4ccccc4)cc3)cc2)CC1O

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 4/20 0.44
PDE4D Q08499 1/20 0.40
ADK P55263 1/20 0.40
HK1 P19367 1/20 0.39
HK2 P52789 1/20 0.39
CHRM2 P08172 2/20 0.39
GALR3 O60755 1/20 0.39
NR2F2 P24468 1/20 0.39
KDM1A O60341 3/20 0.39
MAOB P27338 1/20 0.39
PYGL P06737 1/20 0.39
MMP9 P14780 1/20 0.38
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14234013 1.00 SLC5A2 (0.44) SLC5A2PDE4DADKHK1HK2
SCHEMBL14088381 1.00 SLC5A2 (0.44) SLC5A2PDE4DADKHK1HK2
SCHEMBL14089081 1.00 SLC5A2 (0.44) SLC5A2PDE4DADKHK1HK2
SCHEMBL18025721 1.00 SLC5A2 (0.44) SLC5A2PDE4DADKHK1HK2
SCHEMBL1065647 0.90 PDE4D (0.44) SLC5A2PDE4DADKGALR3NR2F2
SCHEMBL14389130 0.90 PDE4D (0.44) SLC5A2PDE4DADKGALR3NR2F2
SCHEMBL15492630 0.90 PDE4D (0.44) SLC5A2PDE4DADKGALR3NR2F2
SCHEMBL20857297 0.90 PDE4D (0.44) SLC5A2PDE4DADKGALR3NR2F2
SCHEMBL2154637 0.90 PDE4D (0.44) SLC5A2PDE4DADKGALR3NR2F2
SCHEMBL12671725 0.90 PDE4D (0.44) SLC5A2PDE4DADKGALR3NR2F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9416155-B2 Direct sensing of molecular species by polyfluors on a DNA backbone THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2016-08-16 US disclosed
US-20120309107-A1 Direct Sensing of Molecular Species by Polyfluors on a DNA Backbone THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2012-12-06 US disclosed
US-20120309107-A1 Direct Sensing of Molecular Species by Polyfluors on a DNA Backbone THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2012-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120309107-A1 Direct Sensing of Molecular Species by Polyfluors on a DNA Backbone ERCC4, POLL, POLQ SLC5A2 3896/4885PDE4D 2751/4885ADK 1162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.