SCHEMBL14212212

SCHEMBL14212212

Cc1ccc(C(c2ccc(C)cc2)(c2ccc(OC(=O)c3ccccc3)cc2)c2ccc(OC(C)(C)C)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.67
▸ TDP1 Q9NUW8 3/20 0.67
▸ L3MBTL1 Q9Y468 1/20 0.67
▸ ALDH1A1 P00352 4/20 0.48
▸ THRB P10828 1/20 0.48
▸ KMT2A Q03164 7/20 0.48
▸ PKM P14618 1/20 0.48
▸ PARP10 Q53GL7 1/20 0.47
▸ NPSR1 Q6W5P4 2/20 0.46
▸ MEN1 O00255 3/20 0.46
▸ PRSS1 P07477 2/20 0.44
▸ ACR P10323 2/20 0.44
▸ NPC1 O15118 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ RAB9A P51151 2/20 0.43
▸ TSHR P16473 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.42
▸ ELANE P08246 1/20 0.41
▸ PTK2B Q14289 1/20 0.41
▸ RXFP1 Q9HBX9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14627763 0.93 MAPT (0.72) MAPTTDP1L3MBTL1ALDH1A1THRB
SCHEMBL6674207 0.87 TDP1 (0.70) MAPTTDP1L3MBTL1ALDH1A1THRB
SCHEMBL13161726 0.86 MAPT (0.66) MAPTTDP1L3MBTL1ALDH1A1THRB
SCHEMBL13184049 0.86 MAPT (0.66) MAPTTDP1L3MBTL1ALDH1A1THRB
SCHEMBL14151751 0.86 MAPT (0.69) MAPTTDP1L3MBTL1ALDH1A1THRB
SCHEMBL19599191 0.85 PRSS1 (0.56) MAPTTDP1L3MBTL1ALDH1A1KMT2A
SCHEMBL3424218 0.84 MAPT (0.71) MAPTTDP1L3MBTL1ALDH1A1THRB
SCHEMBL26038985 0.83 MAPT (0.69) MAPTTDP1L3MBTL1ALDH1A1THRB
SCHEMBL5705949 0.82 MAPT (0.63) MAPTTDP1L3MBTL1ALDH1A1KMT2A
SCHEMBL14629688 0.82 MAPT (0.54) MAPTTDP1L3MBTL1ALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7378212-B2 Image forming method, photoreceptor KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-05-27 — — US disclosed
US-20070003853-A1 Image forming method, photoreceptor KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-01-04 — — US disclosed
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