⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23270878 | 0.68 | — | — | |
| SCHEMBL2219653 | 0.67 | — | — | |
| SCHEMBL3978359 | 0.64 | — | — | |
| SCHEMBL7019226 | 0.63 | — | — | |
| SCHEMBL7904518 | 0.61 | — | — | |
| SCHEMBL27640437 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL7214172 | 0.61 | — | — | |
| SCHEMBL8479451 | 0.60 | — | — | |
| SCHEMBL4361451 | 0.60 | — | — | |
| SCHEMBL27509140 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12312347-B2 | Azaindole derivative and use thereof as FGFR and C-Met inhibitor | WUXI LIFE FOUNTAIN BIOTECH CO., LTD (CN) | 2025-05-27 | — | — | US | disclosed |
| CN-115667246-A | Crystal form of pyridazine derivative free base and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-112300154-B | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 上海弘翊生物科技有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-115448910-A | Pyridazine derivative inhibitor, and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-114644654-A | Oxidized aryl phosphorus derivative, acid salt or crystal form thereof, and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-114478586-A | Salt or crystal form of inhibitor containing bicyclic derivatives, and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114478528-A | Aroyl-substituted tricyclic compound, preparation method and application thereof | 劲方医药科技(上海)有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-113968846-A | Salts and crystal forms of pyridazine derivatives, and preparation methods and applications of salts and crystal forms | 上海翰森生物医药科技有限公司 | 2022-01-25 | — | — | CN | disclosed |
| US-20210253571-A1 | AZAINDOLE DERIVATIVE AND USE THEREOF AS FGFR AND C-MET INHIBITOR | WUXI LIFE FOUNTAIN BIOTECH CO., LTD (CN) | 2021-08-19 | — | — | US | disclosed |
| CN-113004305-A | Macrocyclic compounds, their preparation and use | 成都倍特药业股份有限公司 | 2021-06-22 | — | — | CN | disclosed |
| CN-112979654-A | Heteroaryl fused ring compound, preparation method and application thereof | 成都倍特药业有限公司 | 2021-06-18 | — | — | CN | disclosed |
| EP-3825314-A1 | AZAINDOLE DERIVATIVE AND USE THEREOF AS FGFR AND C-MET INHIBITOR | Medshine Discovery Inc. (CN) | 2021-05-26 | — | — | EP | disclosed |
| CN-112300154-A | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 上海弘翊生物科技有限公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-111303128-B | Polycyclic compound, preparation method and application thereof | 苏州信诺维医药科技有限公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-111757878-A | Pyridazine derivative inhibitor, and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2020-10-09 | — | — | CN | disclosed |
| CN-111303128-A | Polycyclic compound, preparation method and application thereof | 苏州信诺维医药科技有限公司 | 2020-06-19 | — | — | CN | disclosed |
| US-20110098323-A1 | INHIBITORS OF BACTERIAL BIOFILM FORMATION | MICROBIOTIX, INC. (US) | 2011-04-28 | — | — | US | disclosed |
| EP-2296476-A1 | INHIBITORS OF BACTERIAL BIOFILM FORMATION | Microbiotix, Inc. (US) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009142720-A1 | INHIBITORS OF BACTERIAL BIOFILM FORMATION | MICROBIOTIX, INC. (US) | 2009-11-26 | — | — | WO | disclosed |