SCHEMBL1421336

SCHEMBL1421336

C=CCC=NC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17726071 1.00
SCHEMBL18560730 0.78
SCHEMBL25886313 0.73
SCHEMBL14950218 0.67
SCHEMBL989234 0.67
SCHEMBL15430934 0.67
SCHEMBL24975516 0.65 TSHR (0.52)
SCHEMBL22052031 0.65 TSHR (0.52)
SCHEMBL19155302 0.65 TSHR (0.52)
SCHEMBL19185058 0.65 TSHR (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8829220-B2 Process for preparing dienyl-ruthenium complexes UMICORE AG & CO., KG (DE) 2014-09-09 US claimed
EP-2297173-B1 PROCESS FOR PREPARING DIENYL-RUTHENIUM COMPLEXES UMICORE AG & CO KG (DE) 2013-07-17 EP claimed
US-20110184203-A1 PROCESS FOR PREPARING DIENYL-RUTHENIUM COMPLEXES UMICORE AG & CO. KG (DE) 2011-07-28 US claimed
EP-2297173-A1 PROCESS FOR PREPARING DIENYL-RUTHENIUM COMPLEXES UMICORE AG & CO. KG (DE) 2011-03-23 EP claimed
WO-2009146870-A1 PROCESS FOR PREPARING DIENYL-RUTHENIUM COMPLEXES UMICOR AG & CO. KG (DE) 2009-12-10 WO claimed
US-8829220-B2 Process for preparing dienyl-ruthenium complexes UMICORE AG & CO., KG (DE) 2014-09-09 US disclosed
EP-2297173-B1 PROCESS FOR PREPARING DIENYL-RUTHENIUM COMPLEXES UMICORE AG & CO KG (DE) 2013-07-17 EP disclosed
US-20110184203-A1 PROCESS FOR PREPARING DIENYL-RUTHENIUM COMPLEXES UMICORE AG & CO. KG (DE) 2011-07-28 US disclosed
EP-2297173-A1 PROCESS FOR PREPARING DIENYL-RUTHENIUM COMPLEXES UMICORE AG & CO. KG (DE) 2011-03-23 EP disclosed
WO-2009146870-A1 PROCESS FOR PREPARING DIENYL-RUTHENIUM COMPLEXES UMICOR AG & CO. KG (DE) 2009-12-10 WO disclosed
US-5137889-A Hypotensive agents; coronary vasodilators; calcium antagonists; antiinflammatory agents OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-08-11 US disclosed
US-5034395-A Hypotensive agents, carboxylated dihydropyridines OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-07-23 US disclosed
EP-0145434-A2 Novel dihydropyridine derivatives and process for preparing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1985-06-19 EP disclosed