SCHEMBL14213370

SCHEMBL14213370

C=C(O)c1cc(O)ccc1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.60
CA1 P00915 5/20 0.60
CA2 P00918 5/20 0.60
CA7 P43166 5/20 0.60
CA9 Q16790 5/20 0.60
CA14 Q9ULX7 5/20 0.60
ALOX5 P09917 2/20 0.60
PTGS2 P35354 1/20 0.60
ALDH1A1 P00352 2/20 0.43
TSHR P16473 1/20 0.43
GUSB P08236 1/20 0.43
CHRNA7 P36544 4/20 0.41
GAA P10253 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
MGAM O43451 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
CES2 O00748 1/20 0.39
NR1I2 O75469 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13907075 0.80 CA12 (0.60) CA12CA1CA2CA7CA9
SCHEMBL29899097 0.78 CA12 (0.52) CA12CA1CA2CA7CA9
SCHEMBL9744070 0.78 CA12 (0.52) CA12CA1CA2CA7CA9
SCHEMBL29253806 0.78 CA12 (0.63) CA12CA1CA2CA7CA9
SCHEMBL12677321 0.76 CYP3A4 (0.63) CA12CA1CA2CA7CA9
SCHEMBL15359557 0.76 SRC (0.47) CA12CA1CA2CA7CA9
Gentisic Acid SCHEMBL2053863 0.75 CA1 (1.00) CA12CA1CA2CA7CA9
SCHEMBL6715407 0.75 CA12 (0.60) CA12CA1CA2CA7CA9
Gentisic Acid SCHEMBL3690 0.75 CA1 (1.00) CA12CA1CA2CA7CA9
Gentisic Acid SCHEMBL29349919 0.75 CA1 (1.00) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080119517-A1 COMPOSITIONS AND METHODS FOR PROTECTING AGAINST MITOCHONDRIA COMPONENT-MEDIATED PATHOLOGY CORNELL RESEARCH FOUNDATION, INC. (US) 2008-05-22 US disclosed