Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16372690 | 0.83 | AKR1B1 (0.71) | AKR1B1TNKS2ALOX5MAPTTSHR | |
| SCHEMBL4320087 | 0.82 | POLB (0.65) | POLBATMCHRM2CHRM1CHRM3 | |
| SCHEMBL31252894 | 0.82 | POLB (0.56) | POLBATMAKR1B1MAPTTP53 | |
| Hydrochloric Acid SCHEMBL9829288 | 0.81 | POLB (0.62) | POLBATMCHRM2CHRM1CHRM3 | |
| SCHEMBL9434465 | 0.80 | POLB (0.72) | POLBATMAKR1B1ALOX5MAPT | |
| SCHEMBL31072681 | 0.80 | POLB (0.72) | POLBATMAKR1B1ALOX5MAPT | |
| SCHEMBL7702890 | 0.79 | AKR1B1 (0.55) | AKR1B1TNKS2ALOX5MAPTKDM4E | |
| SCHEMBL223826 | 0.78 | AKR1B1 (0.59) | AKR1B1TNKS2ALOX5MAPTKDM4E | |
| SCHEMBL17263518 | 0.78 | AKR1B1 (0.76) | AKR1B1TNKS2ALOX5CYP1A2TSHR | |
| SCHEMBL15240817 | 0.78 | TNKS2 (0.67) | AKR1B1TNKS2ALOX5MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024246905-A1 | ENZYMES, POLYNUCLEOTIDES ENCODING SAME, AND METHODS OF USING SAME FOR PRODUCING MESCALINE | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2024-12-05 | — | — | WO | disclosed |
| US-7375100-B2 | 2-amino-pyridine derivatives useful for the treatment of diseases | PFIZER INC (US) | 2008-05-20 | — | — | US | disclosed |
| EP-1633715-B1 | 2-(6-AMINO-PYRIDIN-3-YL)-2-HYDROXYETHYLAMINE DERIVATIVES AS BETA 2-ADRENOCEPTORS AGONISTS | PFIZER LTD (GB) | 2007-09-05 | — | — | EP | disclosed |