Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18671890 | 0.82 | NR1I2 (0.44) | CYP2E1NR1I2 | |
| SCHEMBL4351509 | 0.79 | CYP2E1 (0.45) | CYP2E1NR1I2 | |
| SCHEMBL4351506 | 0.79 | CYP2E1 (0.45) | CYP2E1NR1I2 | |
| SCHEMBL17472419 | 0.75 | CYP2E1 (0.42) | CYP2E1NR1I2 | |
| SCHEMBL14214808 | 0.75 | CYP2E1 (0.42) | CYP2E1NR1I2 | |
| SCHEMBL10265311 | 0.73 | CYP2E1 (0.51) | CYP2E1NR1I2 | |
| SCHEMBL4346529 | 0.73 | HTT (0.39) | CYP2E1NR1I2 | |
| SCHEMBL4346533 | 0.73 | HTT (0.39) | CYP2E1NR1I2 | |
| SCHEMBL18735787 | 0.72 | NR1I2 (0.37) | CYP2E1NR1I2 | |
| SCHEMBL9965222 | 0.71 | CYP2E1 (0.49) | CYP2E1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008058393-A1 | THIOPHENE ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC. (CA) | 2008-05-22 | — | — | WO | disclosed |