Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 5/20 | 0.42 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13264678 | 0.85 | APP (0.41) | APP | |
| SCHEMBL10128969 | 0.71 | CYP19A1 (0.47) | CYP19A1MAOAMAOBAPPNQO2 | |
| SCHEMBL9680836 | 0.71 | CYP19A1 (0.78) | CYP19A1MAOAMAOBAPPNQO2 | |
| SCHEMBL7646748 | 0.71 | CYP19A1 (0.78) | CYP19A1MAOAMAOBAPPNQO2 | |
| SCHEMBL9680840 | 0.71 | CYP19A1 (0.78) | CYP19A1MAOAMAOBAPPNQO2 | |
| SCHEMBL65444 | 0.71 | CYP19A1 (0.78) | CYP19A1MAOAMAOBAPPNQO2 | |
| SCHEMBL10459178 | 0.71 | CYP19A1 (0.78) | CYP19A1MAOAMAOBAPPNQO2 | |
| SCHEMBL65443 | 0.71 | CYP19A1 (0.78) | CYP19A1MAOAMAOBAPPNQO2 | |
| SCHEMBL11244660 | 0.71 | CYP19A1 (0.78) | CYP19A1MAOAMAOBAPPNQO2 | |
| SCHEMBL14467533 | 0.70 | MAOB (0.47) | CYP19A1MAOAMAOBMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108840-A1 | Stilbene Derivatives And Their Use For Binding And Imaging Amyloid Plaques | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108840-A1 | Stilbene Derivatives And Their Use For Binding And Imaging Amyloid Plaques | APP, APBA1, PSEN1 | CYP19A1 4622/4885MAOA 1759/4885MAOB 748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.