Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12500837 | 0.83 | MEN1 (0.41) | MEN1KMT2AAPAF1ALDH1A1TDP1 | |
| SCHEMBL12663413 | 0.79 | MEN1 (0.38) | MEN1KMT2AAPAF1ALDH1A1TDP1 | |
| SCHEMBL3503209 | 0.78 | HTT (0.41) | MEN1KMT2AAPAF1ALDH1A1TDP1 | |
| SCHEMBL3503205 | 0.78 | HTT (0.41) | MEN1KMT2AAPAF1ALDH1A1TDP1 | |
| SCHEMBL14705754 | 0.76 | MEN1 (0.47) | MEN1KMT2AAPAF1ALDH1A1TDP1 | |
| SCHEMBL12673483 | 0.74 | TSHR (0.36) | MEN1KMT2AAPAF1ALDH1A1TDP1 | |
| SCHEMBL1893903 | 0.73 | BTK (0.35) | MEN1KMT2AAPAF1TDP1TSHR | |
| SCHEMBL14217483 | 0.73 | TYRO3 (0.31) | — | |
| SCHEMBL25873402 | 0.72 | MEN1 (0.47) | MEN1KMT2AAPAF1ALDH1A1TDP1 | |
| SCHEMBL1893902 | 0.72 | MAOB (0.39) | ALDH1A1TDP1CYP3A4TSHRMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1921078-A1 | MULTIKINASE INHIBITOR | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2008-05-14 | — | — | EP | disclosed |