Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3695547 | 0.84 | PLG (0.33) | SLC6A2SLC6A4SLC6A3PLGPLAT | |
| SCHEMBL4448352 | 0.83 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3634713 | 0.76 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14690635 | 0.71 | — | — | |
| SCHEMBL14975473 | 0.71 | — | — | |
| SCHEMBL10197447 | 0.70 | — | — | |
| SCHEMBL1421753 | 0.69 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23776301 | 0.68 | EPHX1 (0.32) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1421599 | 0.68 | PLG (0.44) | PLGPLATLMNA | |
| SCHEMBL16654044 | 0.68 | SLC6A4 (0.57) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297107-A1 | Ý4-(1-AMINO-ETHYL) -CYCLOHEXYL¨-METHYL-AMINE AND Ý6-(1-AMINO-ETHYL) -TETRAHYDRO- PYRAN-3-YL¨-METHYL-AMINE DERIVATIVES AS ANTIBACTERIALS | Actelion Pharmaceuticals Ltd. (CH) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009147616-A1 | [4-(1-AMINO-ETHYL) -CYCLOHEXYL] -METHYL-AMINE AND [6-(1-AMINO-ETHYL) -TETRAHYDRO- PYRAN-3-YL] -METHYL-AMINE DERIVATIVES AS ANTIBACTERIALS | ACTELION PHARMACEUTICALS LTD (CH) | 2009-12-10 | — | — | WO | disclosed |