Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 18/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | THPO | P40225 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14088094 | 0.88 | SCNN1A (0.47) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL14217510 | 0.88 | SCNN1A (0.47) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL13165922 | 0.87 | SCNN1A (0.51) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL13090587 | 0.86 | SCNN1A (0.42) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL14088104 | 0.85 | SCNN1A (0.47) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL13090594 | 0.85 | SCNN1A (0.47) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL13090593 | 0.85 | SCNN1A (0.47) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL13090591 | 0.85 | SCNN1A (0.47) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL13090585 | 0.85 | SCNN1A (0.47) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL13090600 | 0.85 | SCNN1A (0.47) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375107-B2 | Such as N-(6-aminohexyl)-N'-(3,5-diamino-6-chloropyrazine-2-carbonyl)guanidine Dihydrochloride; for hydration of mucosal surfaces, treating chronic bronchitis, cystic fibrosis, sinusitis, vaginal dryness, dry eye, esophogitis, emphysema, and pneumonia | PARION SCIENCES, INC. (US) | 2008-05-20 | — | — | US | disclosed |