Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5035145 | 1.00 | CNR1 (0.46) | CNR1CNR2ADORA2BKMT2ACYP3A4 | |
| SCHEMBL5034690 | 0.90 | CNR1 (0.40) | CNR1CNR2ADORA2BKMT2APDE2A | |
| SCHEMBL5032570 | 0.90 | CNR1 (0.40) | CNR1CNR2ADORA2BKMT2APDE2A | |
| SCHEMBL5032576 | 0.90 | CNR1 (0.40) | CNR1CNR2ADORA2BKMT2APDE2A | |
| SCHEMBL5035011 | 0.87 | CYP3A4 (0.41) | CNR1CNR2KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL5035195 | 0.87 | CYP3A4 (0.38) | CNR1CNR2ADORA2BKMT2ACYP3A4 | |
| SCHEMBL5035192 | 0.87 | CYP3A4 (0.38) | CNR1CNR2ADORA2BKMT2ACYP3A4 | |
| SCHEMBL5035027 | 0.85 | HTR2C (0.48) | CNR1CNR2KMT2ACYP3A4KDM4E | |
| SCHEMBL5032538 | 0.82 | HTR2C (0.42) | CNR1CNR2ADORA2BKMT2ACYP3A4 | |
| SCHEMBL5032540 | 0.82 | HTR2C (0.42) | CNR1CNR2ADORA2BKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371751-B2 | Thiazole derivatives | HOFFMANN-LA ROCHE INC. (US) | 2008-05-13 | — | — | US | disclosed |