Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 5/20 | 0.33 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.30 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5053560 | 1.00 | QPCT (0.33) | QPCTIP6K1IP6K3HSD11B1 | |
| SCHEMBL5053558 | 1.00 | QPCT (0.33) | QPCTIP6K1IP6K3HSD11B1 | |
| SCHEMBL5053562 | 1.00 | QPCT (0.33) | QPCTIP6K1IP6K3HSD11B1 | |
| SCHEMBL5056779 | 0.91 | QPCT (0.41) | QPCTIP6K1IP6K3HSD11B1 | |
| SCHEMBL14076354 | 0.91 | QPCT (0.41) | QPCTIP6K1IP6K3HSD11B1 | |
| SCHEMBL5056778 | 0.91 | QPCT (0.41) | QPCTIP6K1IP6K3HSD11B1 | |
| SCHEMBL5056780 | 0.91 | QPCT (0.41) | QPCTIP6K1IP6K3HSD11B1 | |
| SCHEMBL5056756 | 0.84 | QPCT (0.36) | QPCTHSD11B1 | |
| SCHEMBL5056751 | 0.84 | QPCT (0.36) | QPCTHSD11B1 | |
| SCHEMBL5056759 | 0.84 | QPCT (0.36) | QPCTHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091945-B1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2014-01-15 | — | — | EP | disclosed |
| WO-2008055947-A1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2008-05-15 | — | — | WO | disclosed |