SCHEMBL14217708

SCHEMBL14217708

OC1CCCCC1/N=C1\NC(=S)N(c2ccc3[nH]cnc3c2)C1c1ccc2nsnc2c1

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
QPCT Q16769 13/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5063891 1.00 QPCT (0.47) QPCT
SCHEMBL5053544 0.91 QPCT (0.56) QPCT
SCHEMBL14076543 0.91 QPCT (0.56) QPCT
SCHEMBL1714482 0.78 QPCT (0.71) QPCT
SCHEMBL14076360 0.77 QPCT (0.39) QPCT
SCHEMBL5062274 0.77 QPCT (0.39) QPCT
SCHEMBL5058053 0.75 QPCT (0.49) QPCT
SCHEMBL14076592 0.75 QPCT (0.49) QPCT
SCHEMBL14076572 0.75 QPCT (0.35) QPCT
SCHEMBL5056963 0.75 QPCT (0.35) QPCT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2091945-B1 NOVEL INHIBITORS OF GLUTAMINYL CYCLASE PROBIODRUG AG (DE) 2014-01-15 EP disclosed
WO-2008055947-A1 NOVEL INHIBITORS OF GLUTAMINYL CYCLASE PROBIODRUG AG (DE) 2008-05-15 WO disclosed