Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 19/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5056876 | 1.00 | QPCT (0.41) | QPCTMMP2ADAMTS5QPCTL | |
| SCHEMBL14076605 | 0.93 | QPCT (0.35) | QPCTMMP2ADAMTS5 | |
| SCHEMBL5056669 | 0.90 | QPCT (0.48) | QPCTQPCTL | |
| SCHEMBL14076710 | 0.90 | QPCT (0.48) | QPCTQPCTL | |
| SCHEMBL5063838 | 0.89 | QPCT (0.42) | QPCTMMP2ADAMTS5QPCTL | |
| SCHEMBL14076637 | 0.89 | QPCT (0.42) | QPCTMMP2ADAMTS5QPCTL | |
| SCHEMBL5053565 | 0.87 | QPCT (0.36) | QPCTQPCTL | |
| SCHEMBL14076609 | 0.86 | QPCT (0.51) | QPCTQPCTL | |
| SCHEMBL5062254 | 0.86 | QPCT (0.51) | QPCTQPCTL | |
| SCHEMBL5063723 | 0.85 | QPCT (0.36) | QPCTMMP2ADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091945-B1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2014-01-15 | — | — | EP | disclosed |
| WO-2008055947-A1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2008-05-15 | — | — | WO | disclosed |