Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 15/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5056989 | 1.00 | QPCT (0.35) | QPCTKDM4EHSD17B10HPGDPPARG | |
| SCHEMBL14076503 | 0.94 | QPCT (0.33) | QPCTKDM4EHSD17B10HPGDPPARG | |
| SCHEMBL5056455 | 0.87 | QPCT (0.37) | QPCTKDM4EHSD17B10HPGDMAPT | |
| SCHEMBL14076562 | 0.87 | QPCT (0.37) | QPCTKDM4EHSD17B10HPGDMAPT | |
| SCHEMBL5058038 | 0.83 | QPCT (0.39) | QPCTKDM4EHSD17B10HPGDMAPT | |
| SCHEMBL14076547 | 0.83 | QPCT (0.39) | QPCTKDM4EHSD17B10HPGDMAPT | |
| SCHEMBL14076426 | 0.83 | QPCT (0.35) | QPCTKDM4EHSD17B10HPGDMAPT | |
| SCHEMBL5134847 | 0.83 | QPCT (0.35) | QPCTKDM4EHSD17B10HPGDMAPT | |
| SCHEMBL14076705 | 0.83 | QPCT (0.41) | QPCTKDM4EHSD17B10HPGDMAPT | |
| SCHEMBL5057106 | 0.83 | QPCT (0.41) | QPCTKDM4EHSD17B10HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091945-B1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2014-01-15 | — | — | EP | disclosed |
| WO-2008055947-A1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2008-05-15 | — | — | WO | disclosed |