Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1632770 | 1.00 | HPGD (0.47) | HPGDSMN1; SMN2GAAKMT2APOLB | |
| SCHEMBL8459065 | 0.94 | HPGD (0.54) | HPGDSMN1; SMN2GAAKMT2ACHRM2 | |
| SCHEMBL8466470 | 0.94 | HPGD (0.54) | HPGDSMN1; SMN2GAAKMT2ACHRM2 | |
| SCHEMBL1633351 | 0.87 | — | — | |
| SCHEMBL10118393 | 0.84 | HPGD (0.45) | HPGDSMN1; SMN2GAAKMT2APOLB | |
| SCHEMBL14301360 | 0.83 | HPGD (0.47) | HPGDSMN1; SMN2GAAKMT2APOLB | |
| SCHEMBL13245892 | 0.83 | HPGD (0.47) | HPGDSMN1; SMN2GAAKMT2APOLB | |
| SCHEMBL13674784 | 0.83 | HPGD (0.47) | HPGDSMN1; SMN2GAAKMT2APOLB | |
| SCHEMBL24172890 | 0.82 | HPGD (0.46) | HPGDSMN1; SMN2GAAKMT2ACHRM2 | |
| SCHEMBL1631843 | 0.82 | DPP4 (0.58) | HPGDSMN1; SMN2GAAKMT2ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008047883-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-04-24 | — | — | WO | disclosed |