Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 14/20 | 0.56 |
| ▸ | LYN | P07948 | 12/20 | 0.56 |
| ▸ | SRC | P12931 | 12/20 | 0.56 |
| ▸ | KDR | P35968 | 12/20 | 0.56 |
| ▸ | INSR | P06213 | 11/20 | 0.56 |
| ▸ | HCK | P08631 | 10/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | BRAF | P15056 | 5/20 | 0.49 |
| ▸ | RAF1 | P04049 | 4/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219018 | 0.94 | LCK (0.57) | LCKLYNSRCKDRINSR | |
| SCHEMBL9967479 | 0.93 | LCK (0.55) | LCKLYNSRCKDRINSR | |
| SCHEMBL9967514 | 0.93 | LCK (0.61) | LCKLYNSRCKDRINSR | |
| SCHEMBL9967466 | 0.92 | LCK (0.46) | LCKLYNSRCKDRINSR | |
| SCHEMBL3590283 | 0.89 | LCK (0.58) | LCKLYNSRCKDRINSR | |
| SCHEMBL13503127 | 0.89 | LCK (0.49) | LCKLYNSRCKDRINSR | |
| SCHEMBL9967510 | 0.89 | LCK (0.49) | LCKLYNSRCKDRINSR | |
| SCHEMBL3587322 | 0.88 | LCK (0.58) | LCKLYNSRCKDRINSR | |
| SCHEMBL9967467 | 0.88 | LCK (0.58) | LCKLYNSRCKDRINSR | |
| SCHEMBL3595899 | 0.88 | LCK (0.61) | LCKLYNSRCKDRINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008042639-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2008-04-10 | — | — | WO | disclosed |