Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 18/20 | 0.43 |
| ▸ | LYN | P07948 | 17/20 | 0.43 |
| ▸ | SRC | P12931 | 17/20 | 0.43 |
| ▸ | KDR | P35968 | 17/20 | 0.43 |
| ▸ | HCK | P08631 | 15/20 | 0.43 |
| ▸ | INSR | P06213 | 15/20 | 0.43 |
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3587031 | 0.94 | LCK (0.45) | LCKLYNSRCKDRHCK | |
| SCHEMBL3584140 | 0.92 | LCK (0.43) | LCKLYNSRCKDRHCK | |
| SCHEMBL3597418 | 0.90 | LCK (0.43) | LCKLYNSRCKDRHCK | |
| SCHEMBL3587058 | 0.90 | LCK (0.43) | LCKLYNSRCKDRHCK | |
| SCHEMBL3587061 | 0.90 | LCK (0.43) | LCKLYNSRCKDRHCK | |
| SCHEMBL3586894 | 0.89 | LCK (0.42) | LCKLYNSRCKDRHCK | |
| SCHEMBL3586891 | 0.89 | LCK (0.42) | LCKLYNSRCKDRHCK | |
| SCHEMBL3595960 | 0.89 | LCK (0.42) | LCKLYNSRCKDRHCK | |
| SCHEMBL3584678 | 0.89 | LCK (0.42) | LCKLYNSRCKDRHCK | |
| SCHEMBL3588725 | 0.89 | LCK (0.42) | LCKLYNSRCKDRHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008042639-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2008-04-10 | — | — | WO | disclosed |