Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 19/20 | 0.58 |
| ▸ | MAP2K2 | P36507 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | BRAF | P15056 | 1/20 | 0.58 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14222536 | 1.00 | MAP2K1 (0.58) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL14222548 | 0.91 | MAP2K1 (0.59) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL14219700 | 0.91 | MAP2K1 (0.59) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL14219613 | 0.90 | MAP2K1 (0.58) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL14219647 | 0.90 | MAP2K1 (0.51) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL14222547 | 0.90 | MAP2K1 (0.58) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL14219749 | 0.89 | MAP2K1 (0.65) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL14219685 | 0.89 | MAP2K1 (0.65) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL14219643 | 0.88 | MAP2K1 (0.57) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 | |
| SCHEMBL14219836 | 0.88 | MAP2K1 (0.58) | MAP2K1MAP2K2MAPK1BRAFMAP2K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908751-A1 | N-hydroxy benzamides with antitumour activity | EOS S.p.A. (IT) | 2008-04-09 | — | — | EP | disclosed |