SCHEMBL14219756 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	MAP2K1	Q02750	20/20	0.48

▸	MAP2K2	P36507	5/20	0.48

▸	BRAF	P15056	1/20	0.42

▸	MAPK1	P28482	1/20	0.42

▸	MAP2K5	Q13163	1/20	0.42

▸	SMC2	O95347	1/20	0.40

▸	EGFR	P00533	1/20	0.40

▸	CSNK2A2	P19784	1/20	0.40

▸	SMC1A	Q14683	1/20	0.40

▸	AAK1	Q2M2I8	1/20	0.40

▸	Q6ZSR9	Q6ZSR9	1/20	0.40

▸	BMP2K	Q9NSY1	1/20	0.40

▸	ABCB11	O95342	1/20	0.36

▸	NQO2	P16083	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14223218	1.00	MAP2K1 (0.48)	MAP2K1MAP2K2BRAFMAPK1MAP2K5
SCHEMBL14223052	0.91	MAP2K1 (0.45)	MAP2K1MAP2K2BRAFMAPK1MAP2K5
SCHEMBL14219843	0.91	MAP2K1 (0.45)	MAP2K1MAP2K2BRAFMAPK1MAP2K5
SCHEMBL14219647	0.91	MAP2K1 (0.51)	MAP2K1MAP2K2BRAFMAPK1MAP2K5
SCHEMBL14219836	0.91	MAP2K1 (0.58)	MAP2K1MAP2K2BRAFMAPK1MAP2K5
SCHEMBL14219659	0.89	MAP2K1 (0.44)	MAP2K1MAP2K2BRAFMAPK1MAP2K5
SCHEMBL14220122	0.89	MAP2K1 (0.48)	MAP2K1MAP2K2BRAFMAPK1MAP2K5
SCHEMBL14219850	0.89	MAP2K1 (0.50)	MAP2K1MAP2K2BRAFMAPK1MAP2K5
SCHEMBL14219753	0.89	MAP2K1 (0.43)	MAP2K1MAP2K2BRAFMAPK1MAP2K5
SCHEMBL14220127	0.88	MAP2K1 (0.50)	MAP2K1MAP2K2BRAFMAPK1MAP2K5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1908751-A1	N-hydroxy benzamides with antitumour activity	EOS S.p.A. (IT)	2008-04-09	—	—	EP	disclosed