SCHEMBL14219903

SCHEMBL14219903

C[C@H](Cc1ccc(CCc2ccc(-c3ccc(Cl)cc3)cc2)cc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.44
SLC6A3 Q01959 1/20 0.44
CYP1A2 P05177 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
PPARG P37231 2/20 0.43
PPARA Q07869 2/20 0.43
MAOB P27338 1/20 0.43
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
SLC2A1 P11166 1/20 0.43
CNR1 P21554 2/20 0.42
CNR2 P34972 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C19 P33261 1/20 0.42
FDFT1 P37268 1/20 0.41
ADAMTS5 Q9UNA0 2/20 0.41
MMP2 P08253 1/20 0.41
SIGMAR1 Q99720 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14219567 1.00 SLC6A2 (0.44) SLC6A2SLC6A3CYP1A2MEN1KMT2A
SCHEMBL14220013 1.00 SLC6A2 (0.44) SLC6A2SLC6A3CYP1A2MEN1KMT2A
SCHEMBL4603704 0.90 SLC6A2 (0.53) SLC6A2SLC6A3CYP1A2MEN1KMT2A
SCHEMBL4603712 0.90 SLC6A2 (0.53) SLC6A2SLC6A3CYP1A2MEN1KMT2A
Ammonia Solution, Strong SCHEMBL8867131 0.88 SLC6A2 (0.52) SLC6A2SLC6A3CYP1A2MEN1KMT2A
SCHEMBL14219885 0.84 POLB (0.51) SLC6A2SLC6A3PPARGPPARAMAOB
SCHEMBL14219563 0.84 POLB (0.51) SLC6A2SLC6A3PPARGPPARAMAOB
SCHEMBL14219378 0.84 POLB (0.51) SLC6A2SLC6A3PPARGPPARAMAOB
SCHEMBL14219894 0.83 MEN1 (0.40) CYP1A2MEN1KMT2APPARGPPARA
SCHEMBL14219888 0.83 MAOB (0.39) CYP1A2MEN1KMT2APPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1650285-B1 Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element SEIMI CHEM KK (JP) 2008-04-30 EP disclosed