Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219960 | 0.91 | GRM2 (0.34) | SIGMAR1IDO1HCRTR1HCRTR2MEN1 | |
| SCHEMBL14219941 | 0.91 | GRM2 (0.34) | SIGMAR1IDO1HCRTR1HCRTR2MEN1 | |
| SCHEMBL14219926 | 0.91 | HCRTR1 (0.38) | SIGMAR1HCRTR1HCRTR2 | |
| SCHEMBL14219956 | 0.91 | HCRTR1 (0.38) | SIGMAR1HCRTR1HCRTR2 | |
| SCHEMBL14219936 | 0.89 | FFAR4 (0.33) | SIGMAR1ESR2FFAR4MEN1KMT2A | |
| SCHEMBL14219448 | 0.89 | FFAR4 (0.33) | SIGMAR1ESR2FFAR4MEN1KMT2A | |
| SCHEMBL14219959 | 0.89 | FFAR4 (0.36) | SIGMAR1FFAR4HCRTR1HCRTR2MEN1 | |
| SCHEMBL14219931 | 0.89 | GRM2 (0.33) | — | |
| SCHEMBL14219925 | 0.89 | FFAR4 (0.36) | SIGMAR1FFAR4HCRTR1HCRTR2MEN1 | |
| SCHEMBL14219961 | 0.89 | GRM2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650285-B1 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | SEIMI CHEM KK (JP) | 2008-04-30 | — | — | EP | disclosed |