Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 20/20 | 0.74 |
| ▸ | PTGER4 | P35408 | 19/20 | 0.74 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219776 | 1.00 | PTGER2 (0.74) | PTGER2PTGER4PTGER3 | |
| SCHEMBL1055415 | 0.85 | PTGER2 (1.00) | PTGER2PTGER4PTGER3 | |
| SCHEMBL4597638 | 0.85 | PTGER2 (1.00) | PTGER2PTGER4PTGER3 | |
| SCHEMBL4597634 | 0.85 | PTGER2 (1.00) | PTGER2PTGER4PTGER3 | |
| SCHEMBL1057561 | 0.83 | PTGER2 (0.80) | PTGER2PTGER4PTGER3 | |
| SCHEMBL1055565 | 0.83 | PTGER2 (0.80) | PTGER2PTGER4PTGER3 | |
| SCHEMBL12960890 | 0.82 | PTGER2 (0.52) | PTGER2PTGER4PTGER3 | |
| SCHEMBL1058786 | 0.82 | PTGER2 (0.94) | PTGER2PTGER4PTGER3 | |
| SCHEMBL14087860 | 0.81 | PTGER2 (1.00) | PTGER2PTGER4PTGER3 | |
| SCHEMBL1057804 | 0.79 | PTGER2 (0.80) | PTGER2PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1439837-B1 | PYRAZOLIDINONE COMPOUNDS AS LIGANDS OF THE PROSTAGLANDIN EP2 AND/OR EP4 RECEPTORS | SERONO LAB (CH) | 2008-04-09 | — | — | EP | disclosed |