Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | MEN1 | O00255 | 9/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | MMP14 | P50281 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14220089 | 0.90 | MEN1 (0.45) | MAPTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL13531849 | 0.89 | MEN1 (0.49) | MAPTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL14220091 | 0.88 | MAPK1 (0.40) | MAPTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL10036075 | 0.85 | MEN1 (0.57) | MAPTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL10623018 | 0.85 | MEN1 (0.57) | MAPTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL10623015 | 0.85 | MEN1 (0.57) | MAPTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL13531851 | 0.82 | MEN1 (0.48) | MAPTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL11881513 | 0.80 | MEN1 (0.64) | MAPTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL11881517 | 0.80 | MEN1 (0.64) | MAPTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL13646350 | 0.78 | APEX1 (0.47) | MAPTMEN1KMT2AMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008046773-A1 | NEGATIVE WORKING, HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2008-04-24 | — | — | WO | disclosed |
| EP-1914068-A1 | Negative working, heat-sensitive lithographic printing plate precursor | Agfa Graphics N.V. (BE) | 2008-04-23 | — | — | EP | disclosed |