SCHEMBL14220486

SCHEMBL14220486

C1=C=Cc2[nH]ccc2C=1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18935533 0.64
SCHEMBL2077044 0.56
SCHEMBL767196 0.48
SCHEMBL12219421 0.46 CCR8 (0.50)
SCHEMBL28900303 0.41
Water SCHEMBL710307 0.32
Water SCHEMBL28573757 0.32
Water SCHEMBL22721755 0.32
Water SCHEMBL22164108 0.32
Water SCHEMBL15906 0.32

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 14456 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122029157-A Bilobalide derivatives for the treatment of neurological diseases and cancers 香港中文大学 2026-05-12 CN claimed
EP-4547732-B1 POLYESTER POLYMER FOR USE IN HAIR CARE SYENSQO SA (BE) 2026-05-06 EP claimed
EP-3856736-B1 NOVEL COMPOUNDS AS NADPH OXIDASE INHIBITORS CALLIDITAS THERAPEUTICS SUISSE SA (CH) 2026-05-06 EP claimed
EP-4721737-A1 USE OF PHARMACEUTICAL COMPOSITION COMPRISING COMPOUND HAVING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE FOR TREATING ANEMIA-RELATED DISEASES Scinnohub Pharmaceutical Co., Ltd. (CN) 2026-04-08 EP claimed
US-12571764-B2 Receptor-based biosensors STATE OF ISRAEL, MINISTRY OF AGRIGULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (A.R.O.) (VOLCANI CENTER) (IL) 2026-03-10 US claimed
US-12559703-B2 Fragrance composition GIVAUDAN SA (CH) 2026-02-24 US claimed
EP-4678638-A1 NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-01-14 EP claimed
US-20250388599-A1 TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS OF USE GENENTECH INC (US) 2025-12-25 US claimed
US-20250387504-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF NOVARTIS AG (CH) 2025-12-25 US claimed
US-12421475-B2 High performing, high impact bloom accord with a top, medium, and base note mixture INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2025-09-23 US claimed
CN-109715617-B Dimethoxyphenyl-substituted indole compounds as inhibitors of TLR7, TLR8 or TLR9 百时美施贵宝公司 2022-04-19 CN claimed
US-11306092-B2 Amino indole compounds useful as TLR inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2022-04-19 US claimed
US-20220112177-A1 KETOAMIDE COMPOUND AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND USE THEREOF FUDAN UNIVERSITY (CN) 2022-04-14 US claimed
CN-113173917-B 1-alkyl-5-tetrazolyl/pyrimidone-1H-indole-3-carbonitrile compound and preparation method and application thereof 沈阳药科大学 2022-04-08 CN claimed
CN-110498789-B Aralkyl piperidine derivative and application thereof in multi-target anti-depression 上海医药工业研究院 2022-04-05 CN claimed
US-20220079135-A1 ATTRACTANTS FOR RATS GRIES GERHARD (CA) 2022-03-17 US claimed
EP-3474841-B1 AR+ BREAST CANCER TREATMENT METHODS ELLIPSES PHARMA LTD (GB) 2022-03-16 EP claimed
CN-108350034-B Antimicrobial polymyxin derived compounds 莫纳什大学 2022-03-11 CN claimed
EP-3957636-A1 FUNGICIDAL OXADIAZOLES FMC Corporation (US) 2022-02-23 EP claimed
WO-2022016690-A1 LUCIFERASE SUBSTRATES, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 山东大学 2022-01-27 WO claimed