Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12829639 | 0.90 | MAPT (0.47) | GAAMAPTMAPK1TDP1KMT2A | |
| SCHEMBL13747809 | 0.90 | BCHE (0.38) | GAAMAPTKMT2AMEN1KIF11 | |
| SCHEMBL12755611 | 0.88 | GAA (0.41) | GAAMAPTMAPK1KMT2ANPSR1 | |
| SCHEMBL1483926 | 0.88 | GAA (0.41) | GAAMAPTMAPK1KMT2ANPSR1 | |
| SCHEMBL1483928 | 0.88 | GAA (0.41) | GAAMAPTMAPK1KMT2ANPSR1 | |
| SCHEMBL12829968 | 0.84 | MAPT (0.39) | GAAMAPTTDP1NPSR1KIF11 | |
| SCHEMBL12829339 | 0.84 | GAA (0.38) | GAAMAPTTDP1KMT2ANPSR1 | |
| SCHEMBL12829641 | 0.83 | MAPT (0.39) | GAAMAPTTDP1KMT2ANPSR1 | |
| SCHEMBL14224278 | 0.83 | GRM5 (0.37) | GAAMAPTKMT2ANPSR1MEN1 | |
| SCHEMBL12829592 | 0.82 | KDR (0.34) | GAAMAPTMAPK1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351841-B2 | Heterocyclic compounds and thrombopoietin receptor activators | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2008-04-01 | — | — | US | disclosed |