Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.51 |
| ▸ | KDM1A | O60341 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14609043 | 0.85 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL6926415 | 0.85 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL30515093 | 0.82 | MEN1 (0.46) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL17086658 | 0.82 | MEN1 (0.46) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL17086730 | 0.82 | MEN1 (0.46) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL17086660 | 0.82 | MEN1 (0.46) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL10964465 | 0.80 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL11105288 | 0.80 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL11105295 | 0.80 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL10964462 | 0.80 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351711-B2 | Tricyclic indanyls as integrin inhibitors | JANSSEN PHARMACEUTICAL, N.V. (BE) | 2008-04-01 | — | — | US | disclosed |