Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1912124 | 0.91 | GAA (0.45) | PTPN1GAAPOLBCTDSP1NPC1 | |
| SCHEMBL1109437 | 0.91 | PTPN1 (0.41) | PTPN1GAAPOLBCTDSP1PPARG | |
| SCHEMBL1912116 | 0.90 | GAA (0.41) | PTPN1GAAPOLBCTDSP1PPARG | |
| SCHEMBL14196108 | 0.89 | — | — | |
| SCHEMBL10286658 | 0.89 | GAA (0.43) | PTPN1GAAPOLBCTDSP1PPARG | |
| SCHEMBL1109454 | 0.89 | KDM4E (0.47) | PTPN1GAAPOLBCTDSP1PPARG | |
| SCHEMBL1109182 | 0.89 | GAA (0.55) | PTPN1GAANPC1ALDH1A1RAB9A | |
| SCHEMBL1912145 | 0.88 | PTPN1 (0.43) | PTPN1GAAPOLBCTDSP1PPARG | |
| SCHEMBL1109275 | 0.88 | PTPN1 (0.39) | PTPN1GAAPOLBCTDSP1HDAC1 | |
| SCHEMBL1109121 | 0.88 | POLB (0.39) | PTPN1GAAPOLBCTDSP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358359-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2008-04-15 | — | — | US | disclosed |