Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254261 | 1.00 | HSD17B10 (0.45) | HSD17B10NR1H2NR1H3SMN1; SMN2NPC1 | |
| SCHEMBL14224497 | 1.00 | HSD17B10 (0.45) | HSD17B10NR1H2NR1H3SMN1; SMN2NPC1 | |
| SCHEMBL4916392 | 0.91 | USP30 (0.42) | HSD17B10NR1H2NR1H3 | |
| SCHEMBL2410020 | 0.91 | USP30 (0.42) | HSD17B10NR1H2NR1H3 | |
| SCHEMBL4916393 | 0.91 | USP30 (0.42) | HSD17B10NR1H2NR1H3 | |
| SCHEMBL14820103 | 0.83 | NR1H2 (0.41) | NR1H2NR1H3SMN1; SMN2HPGDPREP | |
| SCHEMBL6787947 | 0.82 | USP2 (0.41) | HSD17B10NR1H2NR1H3SMN1; SMN2HPGD | |
| SCHEMBL30847117 | 0.82 | NR1H2 (0.42) | HSD17B10NR1H2NR1H3 | |
| SCHEMBL20071487 | 0.82 | NR1H2 (0.42) | HSD17B10NR1H2NR1H3 | |
| SCHEMBL31202888 | 0.81 | HSD17B10 (0.49) | HSD17B10NR1H2NR1H3SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080085884-A1 | Melanin Concentrating Hormone Receptor-1 Antagonist Pyridinones | PFIZER INC | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085884-A1 | Melanin Concentrating Hormone Receptor-1 Antagonist Pyridinones | MCHR1, MCHR2, MC1R | HSD17B10 389/4885NR1H2 755/4885NR1H3 1074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.