Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 19/20 | 0.51 |
| ▸ | HCK | P08631 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13076749 | 0.85 | IGF1R (0.67) | IGF1RMAPK14 | |
| SCHEMBL2936805 | 0.83 | IGF1R (0.74) | IGF1R | |
| SCHEMBL14214983 | 0.80 | IGF1R (0.54) | IGF1R | |
| SCHEMBL14224713 | 0.79 | IGF1R (0.50) | IGF1R | |
| SCHEMBL14224724 | 0.77 | IGF1R (0.46) | IGF1R | |
| SCHEMBL13077177 | 0.77 | IGF1R (0.46) | IGF1R | |
| SCHEMBL2934755 | 0.77 | IGF1R (0.73) | IGF1R | |
| SCHEMBL31572879 | 0.76 | IGF1R (0.80) | IGF1R | |
| SCHEMBL13076750 | 0.76 | IGF1R (0.62) | IGF1R | |
| SCHEMBL13076351 | 0.75 | IGF1R (0.51) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7354933-B2 | Protein kinase inhibitors; antitumor agents; such as 5-methyl-1-quinol-4-ylmethyl-3-(4-trifluoromethanesulfonylphenyl)imidazolidine-2,4-dione trifluoroacetate | AVENTIS PHARMA SA (FR) | 2008-04-08 | — | — | US | disclosed |