Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 19/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MC5R | P33032 | 1/20 | 0.46 |
| ▸ | MC3R | P41968 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13178427 | 0.79 | MC4R (0.62) | MC4RMC5RMC3R | |
| SCHEMBL11891342 | 0.76 | MC4R (0.77) | MC4RMC5RMC3R | |
| SCHEMBL11891345 | 0.76 | MC4R (0.77) | MC4RMC5RMC3R | |
| SCHEMBL14240619 | 0.76 | MC4R (0.77) | MC4RMC5RMC3R | |
| SCHEMBL11891258 | 0.76 | MC4R (0.86) | MC4RMC5RMC3R | |
| SCHEMBL11891231 | 0.76 | MC4R (0.74) | MC4RMC5RMC3R | |
| SCHEMBL14226098 | 0.76 | MC4R (0.66) | MC4R | |
| SCHEMBL11891120 | 0.76 | MC4R (0.77) | MC4RMC5RMC3R | |
| SCHEMBL11891131 | 0.75 | MC4R (0.84) | MC4RMC5RMC3R | |
| SCHEMBL11891329 | 0.75 | MC4R (0.84) | MC4RMC5RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120316201-A1 | NOVEL BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | IPSEN PHARMA S.A.S. (FR) | 2012-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316201-A1 | NOVEL BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | MC4R, MC5R, MC1R | MC4R 1/4885TP53 4401/4885MC5R 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.