Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 3/20 | 0.32 |
| ▸ | BMP1 | P13497 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 3/20 | 0.30 |
| ▸ | CES2 | O00748 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14229024 | 0.92 | CES1 (0.34) | CES1CNR2MMP3FAAHCES2 | |
| SCHEMBL14229598 | 0.87 | CNR2 (0.36) | CES1CNR2BMP1FAAHCES2 | |
| SCHEMBL14229123 | 0.85 | CNR2 (0.40) | CNR2MMP3BMP1 | |
| SCHEMBL14201184 | 0.85 | CNR2 (0.32) | CNR2CNR1 | |
| SCHEMBL14229175 | 0.84 | CA1 (0.38) | CES1CNR2BMP1FAAHCES2 | |
| SCHEMBL14228928 | 0.84 | CNR2 (0.39) | CES1CNR2MMP3BMP1FAAH | |
| SCHEMBL14228930 | 0.82 | CNR2 (0.41) | CES1CNR2MMP3FAAH | |
| SCHEMBL14230126 | 0.80 | TP53 (0.36) | CNR2MMP3BMP1 | |
| SCHEMBL14230127 | 0.80 | PLA2G2C (0.35) | CES1MMP3FAAHCES2 | |
| SCHEMBL14201212 | 0.80 | CNR2 (0.33) | CES1CNR2CNR1BMP1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |