SCHEMBL14229094

SCHEMBL14229094

OC(Cc1cc(Cl)ccc1Cl)(c1ccccc1)C1CNCCO1

nearest known ligand 0.79

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 20/20 0.79
SLC6A4 P31645 9/20 0.39
SLC6A3 Q01959 5/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14203083 1.00 SLC6A2 (0.79) SLC6A2SLC6A4SLC6A3
SCHEMBL14580285 1.00 SLC6A2 (0.79) SLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL5038461 0.99 SLC6A2 (0.78) SLC6A2SLC6A4SLC6A3
SCHEMBL14203012 0.89 SLC6A2 (1.00) SLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL5428490 0.87 SLC6A2 (0.98) SLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL5046050 0.87 SLC6A2 (0.98) SLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL5046054 0.87 SLC6A2 (0.98) SLC6A2SLC6A4SLC6A3
SCHEMBL5042283 0.83 SLC6A2 (0.85) SLC6A2SLC6A4SLC6A3
SCHEMBL14203048 0.82 SLC6A2 (0.83) SLC6A2SLC6A4SLC6A3
SCHEMBL14229089 0.82 SLC6A2 (0.83) SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7354920-B2 Aryl and heteroaryl morpholine derivatives ELI LILLY AND COMPANY (US) 2008-04-08 US disclosed