Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 3/20 | 0.35 |
| ▸ | PPP5C | P53041 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11981957 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1TDP1GBA1PPP5C | |
| SCHEMBL11318242 | 0.88 | GBA1 (0.46) | SMN1; SMN2ALDH1A1TDP1GBA1 | |
| SCHEMBL18102895 | 0.85 | GBA1 (0.43) | SMN1; SMN2GBA1PPP5CBCHE | |
| SCHEMBL18102894 | 0.85 | GBA1 (0.43) | SMN1; SMN2GBA1PPP5CBCHE | |
| SCHEMBL19620378 | 0.83 | TSHR (0.43) | ALDH1A1TDP1BCHE | |
| SCHEMBL19591350 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1TDP1GBA1PPP5C | |
| SCHEMBL18913767 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1TDP1GBA1PPP5C | |
| SCHEMBL14704318 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1TDP1GBA1PPP5C | |
| SCHEMBL12817866 | 0.81 | GBA1 (0.42) | SMN1; SMN2ALDH1A1TDP1GBA1PPP5C | |
| SCHEMBL12446464 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1TDP1GBA1PPP5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2933250-A1 | PHENYL C-GLUCOSIDE DERIVATIVE CONTAINING DEOXYGLUCOSE STRUCTURE, PREPARATION METHOD AND USE THEREOF | Tianjin Institute Of Pharmaceutical Research (CN) | 2015-10-21 | — | — | EP | disclosed |
| US-7361644-B2 | Specific antagonist for both E- and P-selectins | GLYCOMIMETICS, INC. (US) | 2008-04-22 | — | — | US | disclosed |