Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14229250 | 0.88 | MEN1 (0.53) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL4070838 | 0.86 | MEN1 (0.51) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL14229703 | 0.85 | MEN1 (0.52) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL14228856 | 0.83 | KMT2A (0.57) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL4072749 | 0.81 | MEN1 (0.50) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL2198305 | 0.80 | MEN1 (0.54) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL12126612 | 0.79 | MEN1 (0.64) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL17624780 | 0.79 | MEN1 (0.55) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL22597190 | 0.78 | MEN1 (0.57) | MEN1KMT2AKDM4CNPC1RAB9A | |
| SCHEMBL13572536 | 0.76 | MEN1 (0.68) | MEN1KMT2AKDM4CNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008040441-A2 | SILICON DERIVATIVES FOR PET IMAGING | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-04-10 | — | — | WO | disclosed |