Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ASIC3 | Q9UHC3 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20044944 | 0.87 | GRM5 (0.33) | GRM5APPATMTDP1L3MBTL1 | |
| SCHEMBL17263313 | 0.80 | CYP2A6 (0.31) | CYP2A6 | |
| SCHEMBL5683034 | 0.78 | APP (0.55) | GRM5APPATMTDP1L3MBTL1 | |
| SCHEMBL15069878 | 0.77 | CYP2A6 (0.38) | CYP2A6CA12CA2 | |
| SCHEMBL12590007 | 0.75 | ELANE (0.32) | GRM5CYP2A6 | |
| SCHEMBL4586398 | 0.75 | GRM4 (0.33) | CYP2A6 | |
| SCHEMBL442909 | 0.74 | APP (0.50) | GRM5APPATMTDP1L3MBTL1 | |
| SCHEMBL18091340 | 0.74 | APP (0.50) | GRM5APPATMTDP1L3MBTL1 | |
| SCHEMBL762098 | 0.73 | CYP2A6 (0.35) | CYP2A6KDM4E | |
| SCHEMBL762259 | 0.73 | CYP2A6 (0.35) | CYP2A6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9190622-B2 | Hybrid ambipolar TFTs | MERCK PATENT GMBH (DE) | 2015-11-17 | — | — | US | disclosed |
| US-9190622-B2 | Hybrid ambipolar TFTs | MERCK PATENT GMBH (DE) | 2015-11-17 | — | — | US | disclosed |
| WO-2012163464-A1 | HYBRID AMBIPOLAR TFTS | MERCK PATENT GMBH (DE) | 2012-12-06 | — | — | WO | disclosed |