Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.55 |
| ▸ | FNTA | P49354 | 2/20 | 0.49 |
| ▸ | FNTB | P49356 | 2/20 | 0.49 |
| ▸ | SQLE | Q14534 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14236806 | 1.00 | KDM1A (0.55) | KDM1AFNTAFNTBSQLEKMT2A | |
| SCHEMBL14236829 | 1.00 | KDM1A (0.55) | KDM1AFNTAFNTBSQLEKMT2A | |
| SCHEMBL14236860 | 1.00 | KDM1A (0.55) | KDM1AFNTAFNTBSQLEKMT2A | |
| SCHEMBL14236868 | 1.00 | KDM1A (0.55) | KDM1AFNTAFNTBSQLEKMT2A | |
| SCHEMBL14236904 | 1.00 | KDM1A (0.55) | KDM1AFNTAFNTBSQLEKMT2A | |
| SCHEMBL14236905 | 1.00 | KDM1A (0.55) | KDM1AFNTAFNTBSQLEKMT2A | |
| SCHEMBL14236910 | 1.00 | KDM1A (0.55) | KDM1AFNTAFNTBSQLEKMT2A | |
| SCHEMBL14236839 | 1.00 | KDM1A (0.55) | KDM1AFNTAFNTBSQLEKMT2A | |
| SCHEMBL14236805 | 1.00 | KDM1A (0.55) | KDM1AFNTAFNTBSQLEKMT2A | |
| SCHEMBL11551085 | 0.98 | KDM1A (0.53) | KDM1AFNTAFNTBSQLEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981935-B2 | Formation of chiral 4-chromanones using chiral pyrrolidines in the presence of acids | DSM IP ASSETS B.V. (NL) | 2018-05-29 | — | — | US | disclosed |
| US-9815809-B2 | Formation of chiral 4-chromanones using chiral pyrrolidines in the presence of phenols or thiophenols | DSM IP ASSETS B.V. (NL) | 2017-11-14 | — | — | US | disclosed |
| US-9809565-B2 | Formation of chiral 4-chromanones using chiral pyrrolidines in the presence of ureas or thioureas | DSM IP ASSETS B.V. (NL) | 2017-11-07 | — | — | US | disclosed |
| EP-3016940-B1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF PHENOLS OR THIOPHENOLS | DSM IP ASSETS BV (NL) | 2017-04-12 | — | — | EP | disclosed |
| EP-3016939-B1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF ACIDS | DSM IP ASSETS BV (NL) | 2017-03-29 | — | — | EP | disclosed |
| EP-3016941-B1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF UREAS OR THIOUREAS | DSM IP ASSETS BV (NL) | 2017-03-22 | — | — | EP | disclosed |
| EP-3016942-B1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES | DSM IP ASSETS BV (NL) | 2017-03-01 | — | — | EP | disclosed |
| EP-2720996-B1 | HYDROGENATION OF KETONES HAVING AT LEAST A CARBON-CARBON DOUBLE BOND IN THE gamma,delta-POSITION | DSM IP ASSETS BV (NL) | 2016-10-12 | — | — | EP | disclosed |
| US-20160168110-A1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF ACIDS | DSM IP ASSETS B.V. (NL) | 2016-06-16 | — | — | US | disclosed |
| US-20160168111-A1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF PHENOLS OR THIOPHENOLS | DSM IP ASSETS B.V. (NL) | 2016-06-16 | — | — | US | disclosed |
| EP-3016939-A1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF ACIDS | DSM IP Assets B.V. (NL) | 2016-05-11 | — | — | EP | disclosed |
| US-9181163-B2 | Hydrogenation of ketones having at least a carbon-carbon double bond in the γ,δ-position | DSM IP ASSETS B.V. (NL) | 2015-11-10 | — | — | US | disclosed |
| WO-2015001029-A1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF PHENOLS OR THIOPHENOLS | DSM IP ASSETS B.V. (NL) | 2015-01-08 | — | — | WO | disclosed |
| WO-2015001027-A1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF ACIDS | DSM IP ASSETS B.V. (NL) | 2015-01-08 | — | — | WO | disclosed |
| WO-2015001031-A1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES | DSM IP ASSETS B.V. (NL) | 2015-01-08 | — | — | WO | disclosed |
| WO-2015001030-A1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF UREAS OR THIOUREAS | DSM IP ASSETS B.V. (NL) | 2015-01-08 | — | — | WO | disclosed |
| US-20140249321-A1 | HYDROGENATION OF KETONES HAVING AT LEAST A CARBON-CARBON DOUBLE BOND IN THE y, -POSITION | DSM IP ASSETS B.V. (NL) | 2014-09-04 | — | — | US | disclosed |
| EP-2720996-A1 | HYDROGENATION OF KETONES HAVING AT LEAST A CARBON-CARBON DOUBLE BOND IN THE , -POSITION | DSM IP Assets B.V. (NL) | 2014-04-23 | — | — | EP | disclosed |
| WO-2012171969-A1 | HYDROGENATION OF KETONES HAVING AT LEAST A CARBON-CARBON DOUBLE BOND IN THE γ, δ-POSITION | DSM IP ASSETS B.V. (NL) | 2012-12-20 | — | — | WO | disclosed |
| EP-2535323-A1 | Hydrogenation of ketones having at least a carbon-carbon double bond in the gamma-,delta-position | DSM IP Assets B.V. (NL) | 2012-12-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140249321-A1 | HYDROGENATION OF KETONES HAVING AT LEAST A CARBON-CARBON DOUBLE BOND IN THE y, -POSITION | VKORC1, VKORC1L1, CBR1 | KDM1A 839/4885FNTA 792/4885FNTB 798/4885 |
| US-20160168111-A1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF PHENOLS OR THIOPHENOLS | CYP4B1, CYP4F3, CYP4F2 | KDM1A 2675/4885FNTA 1721/4885FNTB 2010/4885 |
| US-20160168110-A1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF ACIDS | CROCC, CBR3, HCCS | KDM1A 3868/4885FNTA 1824/4885FNTB 3608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.