Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.55 |
| ▸ | S1PR5 | Q9H228 | 13/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 11/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 9/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14237208 | 0.90 | S1PR1 (0.54) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL14237187 | 0.90 | S1PR1 (0.53) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL1334354 | 0.89 | S1PR1 (0.70) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL14237345 | 0.87 | S1PR1 (0.56) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL1335776 | 0.86 | S1PR1 (0.58) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL14237224 | 0.86 | S1PR1 (0.49) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL14237168 | 0.85 | S1PR1 (0.51) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL14237156 | 0.85 | S1PR1 (0.49) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL14237169 | 0.84 | S1PR1 (0.51) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL14237218 | 0.83 | S1PR1 (0.49) | S1PR1S1PR5S1PR4S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382211-B1 | PYRAZOLE-I, 2, 4 -OXAD IAZOLE DERIVATIVES AS S.PHING0SINE-1-PH0SPHATE AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2012-12-19 | — | — | EP | claimed |