Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 16/20 | 0.50 |
| ▸ | CFD | P00746 | 2/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3461201 | 0.90 | ATR (0.52) | ATR | |
| SCHEMBL3462316 | 0.88 | ATR (0.49) | ATRTYRO3 | |
| SCHEMBL3460139 | 0.88 | ATR (0.49) | ATRTYRO3 | |
| SCHEMBL3462251 | 0.87 | ATR (0.51) | ATRCFD | |
| SCHEMBL3462639 | 0.87 | ATR (0.51) | ATRCFD | |
| SCHEMBL14237336 | 0.85 | PIK3CD (0.49) | ATRTYRO3 | |
| SCHEMBL3462894 | 0.83 | ATR (0.49) | ATRCFDTYRO3 | |
| SCHEMBL3462242 | 0.83 | ATR (0.49) | ATRCFDTYRO3 | |
| SCHEMBL3459993 | 0.83 | ATR (0.52) | ATRCFDTYRO3 | |
| SCHEMBL14237222 | 0.83 | ATR (0.52) | ATRCFDTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501514-B1 | PROTEIN KINASE MODULATORS AND METHODS OF USE | EXELIXIS INC (US) | 2012-12-19 | — | — | EP | claimed |