Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.45 |
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14999205 | 0.89 | MAPT (0.46) | MAPK14CSNK2A2CSNK2A1KDM4EMEN1 | |
| SCHEMBL14239143 | 0.88 | ESR2 (0.46) | ESR2ESR1MAPK14KDM4EMEN1 | |
| SCHEMBL14999203 | 0.82 | LIMK1 (0.48) | MAPK14CSNK2A2CSNK2A1KDM4EMEN1 | |
| SCHEMBL14239589 | 0.82 | CSNK2A2 (0.42) | MAPK14CSNK2A2CSNK2A1MEN1KMT2A | |
| SCHEMBL14999206 | 0.80 | STIM1 (0.52) | MAPK14CSNK2A2CSNK2A1MEN1KMT2A | |
| SCHEMBL14239588 | 0.76 | MEN1 (0.40) | MAPK14CSNK2A2CSNK2A1MEN1KMT2A | |
| SCHEMBL14999204 | 0.76 | KDM4E (0.49) | MAPK14KDM4EMEN1KMT2ATP53 | |
| SCHEMBL14999199 | 0.73 | STIM1 (0.46) | MAPK14KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL16526141 | 0.70 | LIMK1 (0.72) | MAPK14LIMK1 | |
| SCHEMBL14239590 | 0.70 | STIM1 (0.40) | MAPK14CSNK2A2CSNK2A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170951-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2012-12-13 | — | — | WO | disclosed |