Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12645238 | 0.90 | CSNK2A1 (0.47) | CSNK2A1KDM4ECSNK2BALDH1A1HPGD | |
| SCHEMBL2029597 | 0.90 | CSNK2A1 (0.47) | CSNK2A1KDM4EMAPK1CSNK2BHPGD | |
| SCHEMBL2029600 | 0.90 | CSNK2A1 (0.47) | CSNK2A1KDM4EMAPK1CSNK2BHPGD | |
| SCHEMBL2029594 | 0.90 | CSNK2A1 (0.47) | CSNK2A1KDM4EMAPK1CSNK2BHPGD | |
| SCHEMBL12644694 | 0.89 | CSNK2A1 (0.47) | CSNK2A1MAPK1ALDH1A1PIK3CAPRKDC | |
| SCHEMBL12645733 | 0.88 | CSNK2A1 (0.46) | CSNK2A1KDM4EMAPK1CSNK2BALDH1A1 | |
| SCHEMBL12644827 | 0.88 | CSNK2A1 (0.51) | CSNK2A1KDM4EMAPK1CSNK2BALDH1A1 | |
| SCHEMBL12645639 | 0.88 | CSNK2A1 (0.46) | CSNK2A1PRKDC | |
| SCHEMBL12645246 | 0.88 | CSNK2A1 (0.46) | CSNK2A1KDM4ECSNK2BALDH1A1HPGD | |
| SCHEMBL12644771 | 0.87 | CSNK2B (0.42) | CSNK2A1KDM4EMAPK1CSNK2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170827-A2 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2012-12-13 | — | — | WO | disclosed |